Subutex 8mg are sublingual tablets containing buprenorphine (as buprenorphine hydrochloride) in the strength of 8mg. It comes as an uncoated oval flat beveled edged white-colored tablet in the dimensions of 14 mm x 7 mm having the imprint of “B8” on one side. The inactive ingredients of Subutex 8mg tablets are monohydrate lactose, mannitol, maize starch, citric acid, sodium citrate, povidone K30, and magnesium stearate.
Uses of Subutex 8mg
Subutex 8mg tablets are useful as the substitution treatment for opioid drug dependence. The induction treatment is helpful as a part of a complete plan, including psychosocial support and counseling therapy.
Dosage of Subutex 8mg
Administer Subutex sublingually as a single daily dose.
As the Subutex 8mg tablets do not contain naloxone, they are useful for induction only.
Before the induction treatment, doctors take into consideration the type of opioid dependence (short-acting or long-acting opioids), degree or level of opioid addiction, and the time since last opioid use.
For the patients dependent on short-acting opioid products or heroin, start the treatment only when clear signs of opioid withdrawal appear, not less than 6 hours before the last opioid use.
For the patients taking long-acting opioid products or methadone, reduce the daily dose of methadone to 30mg per day before starting the dosage of Subutex 8mg. Subutex may bring out the withdrawal symptoms in the methadone dependent patients. Give the initial dose only when the signs of moderate opioid withdrawal appear, generally after 24 hours of last methadone dose (due to the half-life of methadone).
Initiate the daily dose of Subutex with 0.8mg to 4mg given as a single sublingual dose.
Increase the doses of medication to achieve maximum relief for the individual patient. Do not exceed the daily dose of 4 tablets of Subutex 8mg per day.
Reassess the dosage regime according to the patient’s needs and psychological status. Reduce the doses gradually after a satisfactory period of stabilization.
Side Effects of the product :
The most common side effects of Subutex 8mg tablets include:
- Drug withdrawal syndrome
The less common side effects of Subutex 8mg include:
- Decrease appetite
- Toot disorder
- Gastrointestinal disorder
- Muscle spasm